À propos de ce cours
4.7
370 notes
81 avis
Spécialisation

Course 1 of 7 in the

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100 % en ligne

Commencez dès maintenant et apprenez aux horaires qui vous conviennent.
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Dates limites flexibles

Réinitialisez les dates limites selon votre disponibilité.
Niveau débutant

Niveau débutant

Heures pour terminer

Approx. 13 heures pour terminer

Recommandé : 4-10 hours/week...
Langues disponibles

Anglais

Sous-titres : Anglais

Compétences que vous acquerrez

BioinformaticsBioinformatics AlgorithmsAlgorithmsPython Programming
Spécialisation

Course 1 of 7 in the

100 % en ligne

100 % en ligne

Commencez dès maintenant et apprenez aux horaires qui vous conviennent.
Dates limites flexibles

Dates limites flexibles

Réinitialisez les dates limites selon votre disponibilité.
Niveau débutant

Niveau débutant

Heures pour terminer

Approx. 13 heures pour terminer

Recommandé : 4-10 hours/week...
Langues disponibles

Anglais

Sous-titres : Anglais

Programme du cours : ce que vous apprendrez dans ce cours

Semaine
1
Heures pour terminer
3 heures pour terminer

Week 1: Welcome!

<p>Welcome to class!</p><p>This course will focus on two questions at the forefront of modern computational biology, along with the algorithmic approaches we will use to solve them in parentheses:</p><ol><li>Weeks 1-2: Where in the Genome Does DNA Replication Begin? (<em>Algorithmic Warmup</em>)</li><li>Weeks 3-4: Which DNA Patterns Play the Role of Molecular Clocks? (<em>Randomized Algorithms</em>)</li></ol><p>Week 5 will consist of a Bioinformatics Application Challenge in which you will get to apply software for finding DNA motifs to a real biological dataset.</p><p>Each of the two chapters in the course is accompanied by a Bioinformatics Cartoon created by Randall Christopher and serving as a chapter header in the Specialization's bestselling <a href="http://bioinformaticsalgorithms.com" target="_blank">print companion</a>. You can find the first chapter's cartoon at the bottom of this message. What does a cryptic message leading to buried treasure have to do with biology? We hope you will join us to find out!</p><p><img src="http://bioinformaticsalgorithms.com/images/cover/replication_cropped.jpg" title="Image: http://bioinformaticsalgorithms.com/images/cover/chapter1_cropped.jpg" width="500"></p><p><a href="http://compeau.cbd.cmu.edu" target="_blank"><img src="http://bioinformaticsalgorithms.com/images/Compeau_caricature.jpg" width ="150"></a> <a href="http://cseweb.ucsd.edu/~ppevzner/" target="_blank"><img src="http://bioinformaticsalgorithms.com/images/Pevzner_caricature.jpg" width ="150"></a></p><p>Phillip and Pavel</p>...
Reading
3 videos (Total 21 min), 3 lectures, 3 quiz
Video3 vidéos
Where in the Genome Does DNA Replication Begin? (Part 1) (11:37)11 min
Where in the Genome Does DNA Replication Begin? (Part 2) (06:24)6 min
Reading3 lectures
Course Details10 min
Week 1 FAQs (Optional)0
What is Pseudocode? (Optional)1 min
Quiz1 exercice pour s'entraîner
Week 1 Quiz15 min
Semaine
2
Heures pour terminer
3 heures pour terminer

Week 2: Finding Replication Origins

<p>Welcome to Week 2 of class!</p> <p>This week, we will examine the biological details of how DNA replication is carried out in the cell. We will then see how to use these details to help us design an intelligent algorithmic approach looking for the replication origin in a bacterial genome.</p>...
Reading
2 videos (Total 13 min), 1 lecture, 3 quiz
Video2 vidéos
Where in the Genome Does DNA Replication Begin? (Part 4) (04:10)4 min
Reading1 lecture
Week 2 FAQs (Optional)0
Quiz1 exercice pour s'entraîner
Week 2 Quiz15 min
Semaine
3
Heures pour terminer
4 heures pour terminer

Week 3: Hunting for Regulatory Motifs

<p>Welcome to Week 3 of class!</p> <p>This week, we begin a new chapter, titled "Which DNA Patterns Play the Role of Molecular Clocks?" At the bottom of this message is this week's Bioinformatics Cartoon. &nbsp;What does a late night casino trip with two 18th Century French mathematicians have in common with finding molecular clocks? &nbsp;Start learning to find out...</p> <p><img src="https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter3_final.jpg" title="Image: https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter3_final.jpg" width="528"></p>...
Reading
3 videos (Total 23 min), 1 lecture, 3 quiz
Video3 vidéos
From Implanted Patterns to Regulatory Motifs (Part 2) (05:06)5 min
From Implanted Patterns to Regulatory Motifs (Part 3) (07:22)7 min
Reading1 lecture
Week 3 FAQs (Optional)0
Quiz1 exercice pour s'entraîner
Week 3 Quiz15 min
Semaine
4
Heures pour terminer
3 heures pour terminer

Week 4: How Rolling Dice Helps Us Find Regulatory Motifs

<p>Welcome to Week 4 of class!</p> <p>Last week, we encountered a few introductory motif-finding algorithms. This week, we will see how to improve upon these motif-finding approaches by designing randomized algorithms that can "roll dice" to find motifs.</p>...
Reading
3 videos (Total 26 min), 1 lecture, 3 quiz
Video3 vidéos
How Rolling Dice Helps Us Find Regulatory Motifs (Part 2) (05:37)5 min
How Rolling Dice Helps Us Find Regulatory Motifs (Part 3) (07:46)7 min
Reading1 lecture
Week 4 FAQs (Optional)0
Quiz1 exercice pour s'entraîner
Week 4 Quiz15 min
4.7
81 avisChevron Right
Orientation de carrière

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Avantage de carrière

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Meilleurs avis

par LLNov 13th 2017

Very tough but rewarding class. The programming part was easy, the algorithms kicked my butt. Love the challenge and can't wait to take the rest!!! Such an interesting field!

par MPDec 4th 2017

Nice and recommended.\n\n(The final exam was a bit tedious though, with many points repeatedly given simply for "uploading the logo" and not much creative leeway)

Enseignants

Avatar

Pavel Pevzner

Professor
Department of Computer Science and Engineering
Avatar

Phillip Compeau

Visiting Researcher
Department of Computer Science & Engineering

À propos de University of California San Diego

UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 10 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom—life is their laboratory....

À propos de la Spécialisation Bioinformatics

Join Us in a Top 50 MOOC of All Time! How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all species on Earth? When you complete this Specialization, you will learn how to answer many questions in modern biology that have become inseparable from the computational approaches used to solve them. You will also obtain a toolkit of existing software resources built on these computational approaches and that are used by thousands of biologists every day in one of the fastest growing fields in science. Although this Specialization centers on computational topics, you do not need to know how to program in order to complete it. If you are interested in programming, we feature an "Honors Track" (called "hacker track" in previous runs of the course). The Honors Track allows you to implement the bioinformatics algorithms that you will encounter along the way in dozens of automatically graded coding challenges. By completing the Honors Track, you will be a bioinformatics software professional! Learn more about the Bioinformatics Specialization (including why we are wearing these crazy outfits) by watching our introductory video. You can purchase the Specialization's print companion, Bioinformatics Algorithms: An Active Learning Approach, from the textbook website. Our first course, "Finding Hidden Messages in DNA", was named a top-50 MOOC of all time by Class Central!...
Bioinformatics

Foire Aux Questions

  • Une fois que vous êtes inscrit(e) pour un Certificat, vous pouvez accéder à toutes les vidéos de cours, et à tous les quiz et exercices de programmation (le cas échéant). Vous pouvez soumettre des devoirs à examiner par vos pairs et en examiner vous-même uniquement après le début de votre session. Si vous préférez explorer le cours sans l'acheter, vous ne serez peut-être pas en mesure d'accéder à certains devoirs.

  • Lorsque vous vous inscrivez au cours, vous bénéficiez d'un accès à tous les cours de la Spécialisation, et vous obtenez un Certificat lorsque vous avez réussi. Votre Certificat électronique est alors ajouté à votre page Accomplissements. À partir de cette page, vous pouvez imprimer votre Certificat ou l'ajouter à votre profil LinkedIn. Si vous souhaitez seulement lire et visualiser le contenu du cours, vous pouvez accéder gratuitement au cours en tant qu'auditeur libre.

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