This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems?
Ce cours fait partie de la Spécialisation Biologie des systèmes et biotechnologie
Offert par
Spécialisation Biologie des systèmes et biotechnologieIcahn School of Medicine at Mount SinaiÀ propos de ce cours
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Offert par
Icahn School of Medicine at Mount Sinai
The Icahn School of Medicine at Mount Sinai, in New York City is a leader in medical and scientific training and education, biomedical research and patient care.
Programme de cours : ce que vous apprendrez dans ce cours
Systems Level Reasoning | Molecules to Pathways
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Pathways to Networks | Physical Forces and Electrical Activity in Cell Biology
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Mathematical Representations of Cell Biological Systems | Simulations of Cell Biological Systems
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Experimental Technologies | Network Building and Analysis
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Avis
- 5 stars56,84 %
- 4 stars25,28 %
- 3 stars8,74 %
- 2 stars5,13 %
- 1 star3,99 %
Meilleurs avis pour INTRODUCTION À LA BIOLOGIE DES SYSTÈMES
Nice course, a little boring at the beginning with so much data about cell signaling, (kinases names, and specific routes).
It's a challenging subject. Don't expect to walk away from the course with a complete grasp of systems biology. However, this course is a fantastic place to start.
Coursera make it different...
I'm pretty lucky to find a systems biology course like this.
that corse was really beneficial and useful for me. Thanks a lot
À propos du Spécialisation Biologie des systèmes et biotechnologie
Design systems-level experiments using appropriate cutting edge techniques, collect big data, and analyze and interpret small and big data sets quantitatively.
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