This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems?
Ce cours fait partie de la Spécialisation Biologie des systèmes et biotechnologie
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Spécialisation Biologie des systèmes et biotechnologieIcahn School of Medicine at Mount SinaiÀ propos de ce cours
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Programme de cours : ce que vous apprendrez dans ce cours
Systems Level Reasoning | Molecules to Pathways
Pathways to Networks | Physical Forces and Electrical Activity in Cell Biology
Mathematical Representations of Cell Biological Systems | Simulations of Cell Biological Systems
Experimental Technologies | Network Building and Analysis
Avis
- 5 stars56,41 %
- 4 stars25,47 %
- 3 stars8,86 %
- 2 stars5,09 %
- 1 star4,15 %
Meilleurs avis pour INTRODUCTION À LA BIOLOGIE DES SYSTÈMES
Very useful course in order to learn the basics in systems biology. You only need some training in biology to understand the concepts but the course is easy to follow and very complete.
It's a challenging subject. Don't expect to walk away from the course with a complete grasp of systems biology. However, this course is a fantastic place to start.
Nice course, a little boring at the beginning with so much data about cell signaling, (kinases names, and specific routes).
This online course is very helpful and very educational.
À propos du Spécialisation Biologie des systèmes et biotechnologie
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