Spécialisation Biologie des systèmes et biotechnologie
Expertise for Professionals and Students in Biotechnology and Biomedical Data Sciences. Learn Methodologies in Systems Biology Including: Bioinformatics, Dynamical Modeling, Genomics, Network and Statistical Modeling, Proteomics, Omics Technologies Single Cell Research Technologies
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Compétences que vous acquerrez
À propos de ce Spécialisation
Certaines connaissances prérequises.
Certaines connaissances prérequises.
Cette Spécialisation compte 6 cours
Introduction à la biologie des systèmes
This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems?
Méthodes expérimentales dans la biologie des systèmes
Learn about the technologies underlying experimentation used in systems biology, with particular focus on RNA sequencing, mass spec-based proteomics, flow/mass cytometry and live-cell imaging.
Analyse des réseaux dans la biologie systémique
An introduction to data integration and statistical methods used in contemporary Systems Biology, Bioinformatics and Systems Pharmacology research. The course covers methods to process raw data from genome-wide mRNA expression studies (microarrays and RNA-seq) including data normalization, differential expression, clustering, enrichment analysis and network construction. The course contains practical tutorials for using tools and setting up pipelines, but it also covers the mathematics behind the methods applied within the tools. The course is mostly appropriate for beginning graduate students and advanced undergraduates majoring in fields such as biology, math, physics, chemistry, computer science, biomedical and electrical engineering. The course should be useful for researchers who encounter large datasets in their own research. The course presents software tools developed by the Ma’ayan Laboratory (http://labs.icahn.mssm.edu/maayanlab/) from the Icahn School of Medicine at Mount Sinai, but also other freely available data analysis and visualization tools. The ultimate aim of the course is to enable participants to utilize the methods presented in this course for analyzing their own data for their own projects. For those participants that do not work in the field, the course introduces the current research challenges faced in the field of computational systems biology.
Méthodes de modélisation dynamique pour la biologie des systèmes
An introduction to dynamical modeling techniques used in contemporary Systems Biology research.
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Icahn School of Medicine at Mount Sinai
The Icahn School of Medicine at Mount Sinai, in New York City is a leader in medical and scientific training and education, biomedical research and patient care.
Foire Aux Questions
Quelle est la politique de remboursement ?
Puis-je m'inscrire à un seul cours ?
Une aide financière est-elle possible ?
Puis-je suivre le cours gratuitement ?
Ce cours est-il vraiment accessible en ligne à 100 % ? Dois-je assister à certaines activités en personne ?
Puis-je obtenir des crédits universitaires si je réussis la Spécialisation ?
Puis-je obtenir des crédits universitaires si je réussis la Spécialisation ?
What background knowledge is necessary?
Do I need to take the courses in a specific order?
Will I earn university credit for completing the Systems Biology and Biotechnology Specialization?
What will I be able to do upon completing the Systems Biology and Biotechnology Specialization?
What software will I need to complete the assignments?
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