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Avis et commentaires pour d'étudiants pour Finding Hidden Messages in DNA (Bioinformatics I) par Université de Californie à San Diego

808 évaluations
187 avis

À propos du cours

Named a top 50 MOOC of all time by Class Central! This course begins a series of classes illustrating the power of computing in modern biology. Please join us on the frontier of bioinformatics to look for hidden messages in DNA without ever needing to put on a lab coat. In the first half of the course, we investigate DNA replication, and ask the question, where in the genome does DNA replication begin? We will see that we can answer this question for many bacteria using only some straightforward algorithms to look for hidden messages in the genome. In the second half of the course, we examine a different biological question, when we ask which DNA patterns play the role of molecular clocks. The cells in your body manage to maintain a circadian rhythm, but how is this achieved on the level of DNA? Once again, we will see that by knowing which hidden messages to look for, we can start to understand the amazingly complex language of DNA. Perhaps surprisingly, we will apply randomized algorithms, which roll dice and flip coins in order to solve problems. Finally, you will get your hands dirty and apply existing software tools to find recurring biological motifs within genes that are responsible for helping Mycobacterium tuberculosis go "dormant" within a host for many years before causing an active infection....

Meilleurs avis

29 juil. 2018

This course is very very good. Challenging at times. It does not hold your hand at all times and sometimes requires research to solve some of the problems, but I like the community and the approach.

10 sept. 2019

The material of the course is simply exquisitely presented. The concepts are clear, easy to grasp. You won't be a bioinformatician after doing this course, but you'll make the first step.

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1 - 25 sur 182 Avis pour Finding Hidden Messages in DNA (Bioinformatics I)

par Saif-AlDin

3 août 2018

I have received financial aid because I was interested in the bioinformatics field and was reading alot about it and wanted to start my first course, it was my biggest mistake that I have chosen this course. It is awfully explained, terrible accent, basically a course with 50% information for beginners and 50% for coders and the quiz for week 2 just pumped my blood pressure to the roof, this course is in no way to be called for beginners and the interactive text is a mess and it is no way as a biotechnologist that I am going to recommend this course to anyone !, I need to apologize for coursera company for giving me aid for this COURSE !

note : this course is basically like a money grab, it is not enough that you are on their course they actually from Minute one advertise for their book vol 1 and 2... such a joke.

All in all I am stopping this course because the knowledge I am gaining from this course is 1 on the scale of 10, and the amount of confusion and frustration and disappointment I am getting is 10 on the scale of 10 !!

I really hope coursera can forgive my dropping out of this course and allows me to get a financial aid at an actual course

par Melinda B

30 avr. 2019

This course is really frustrating if you are not a computer scientist.

The 'language-neutral pseudocode' given on the computer science tasks is buggy and hard to figure out and there is no support or solutions. This course is just hours spent rerunning your code by brute force to pray you get to their answer to pass.

Work is not explained well. The only reason to take this course is that its supported by UCSD.

par Laura L

13 nov. 2017

Very tough but rewarding class. The programming part was easy, the algorithms kicked my butt. Love the challenge and can't wait to take the rest!!! Such an interesting field!

par Radek S

26 avr. 2020

The strong accent of one of the teachers made me just leave the course after the first video, sadly.

par Juris L

30 juil. 2018

This course is very very good. Challenging at times. It does not hold your hand at all times and sometimes requires research to solve some of the problems, but I like the community and the approach.

par Gener A R

7 avr. 2019

Good course, very solid community.

par Barry L K

9 juin 2016

Unfortunately, as often happens, what is "simple" and basic for one is not that for another. This course presumes a comfortableness with coding that I simply do not possess as a teacher of high school science. Please try and develop a true introductory course that normal, non-programmers can access. Thanks!

par Tuğrul G

17 avr. 2020

Videos and content are unrelated. Stepik application doesn't accept our answers even if it is true!

par Deleted A

30 mars 2020

For computer scientists, not biologists

par FENG C

5 avr. 2020

not for beginners

par Marek B

17 sept. 2017

This course was fun and very rewarding, I feel like I learned a lot about both algorithms and biology.

I have completed the Honors track---coming from a computer science background the algorithmic parts were mostly easy for me (I generally came up with all the algorithms on my own) but still fun to work through, especially because of their connection to real-world biology problems.

Interesting as the biological motivations had been they really only scratched the surface and made me want to learn more. For that I worked through the online MIT biology course [1] led by Eric Lander (of the Human Genome Project fame) that I cannot recommend enough.


par Federico R

28 sept. 2016


Very well explained. I'm a molecular biologist seeking for some programming skills and understanding of the basics of the everydays tools. I've found some caveats in the coding problems from stepik but I understand that's difficult to give complete and exact explanations to everyone and every programming language that someone can use. Besides that everything's perfect! And recommended!

par Philipp M

10 sept. 2017

This course is really educational and well designed. The course content is well structured and clearly described. If you have no previous knowledge in this topic, I would recommend to start with the beginner's course "Biology Meets Programming: Bioinformatics for Beginners" in order to be prepared for concepts like pseudocode or the computational way of thinking in general.

Definitely recommended!

par Sakshar C

29 mai 2020

The course was very well designed to engage any one with CS background to get highly motivated to learning Bioinformatics. Personally, I have found the humorous representations of the instructors very appealing and also enjoyed the programming challenges. Moreover, it helped me to develop an insight to connect my CS knowledge for solving Biological problems. I am looking forward to completing the full specialization.

par Darius F

4 févr. 2018

Well made introduction into the field. Good programming exercises which are easy to medium difficulty with a computer science background. It feels like they put a lot of thought into the course structure. Some of the biological explanations are too brief without a biological background, and I would guess the same for students without a computer science background regarding the exercises.

par Victoria T A

29 janv. 2021

This is an amazing course for me and a perfect choice at that. I am a pure biologist and the computer science aspect bit was indeed challenging being the first time of my doing such ever. I will be starting my PhD (topic - antibiotic resistance) in a few weeks that requires knowledge & skills in bioinformatics. I believe this course has sure prepared me for what is to come. Thank you!

par Robert K

30 août 2016

This was fantastic course! I've never experienced such passion in an online course. I've learned so much, and I am striving for more... fortunately this is just the beginning. No wonder it has been proclaimed as one of the 50 most popular MOOCs of all time. Not because it is popular you should take it, it has become popular because it is just marvellous.

Worth it!

par bob n

16 juil. 2020

Thoroughly enjoyed the course. Was a big help to have taken the intro class first. Instructors did a reasonable job of leading one through the material. Would have preferred more lecture, less reading, but not enough to knock a star off the rating. Material well organized. As some with an engineering background, the biology was mostly well explained.

par Ranakombu K K D S

12 avr. 2020

A well-structured and amazing course that provides a wealth of knowledge in bioinformatics including an optional honors track for programming. Thoroughly enjoyed it and excited to continue with the rest of the Specialization! A big thank you to the creators of this brilliant course. Simply one of the best courses on Coursera!

par Comfort A

13 sept. 2020

I am so overwhelmed. I learnt a whole lottttt. I learnt how to create motif logos, identify ori and terminus using skew diagrams, amongst others. As a biologist, I was really discouraged at the beginning because of the series of referring links, but I am happy that I could see the end of the course. Thanks for the content.

par Tirthankar S

2 avr. 2018

One of the best online courses I've ever taken. Since I come from a biotechnology background, this course was particularly relevant for me in terms of its depth and thoroughness. Seriously considering a future in computational biology, thanks to this course.

par Manuel A

25 juil. 2016

Very good course, but at the same time very hard. Unless you have quite a bit of experience programing, be prepared to spend at least 15 hours a week working on this class. The good news is that if you do spend that time, you will learn a lot.

par Hercules P N

9 mai 2017

Excellent course. It can be tough at times but it is amazingly accessible to all who are genuinely interested. The final assignment was very well prepared and gave a real hands-on experience that puts the course into practice.

par Krishnendu S

28 mars 2019

Exceptionally beautiful course. Must be for those want to start career in bioinformatics. But prior basic knowledge in any programming language would be appropriate if someone wants to extract every aspect of this course.

par Yasmine E H

4 juil. 2020

I really liked this course and definitely learned a lot. However, I wish that more guidance was provided such as the professors, and not just the peers, answering our questions when Stepik's explanation was not enough.