À propos de ce cours
4.9
990 ratings
266 reviews
Medical Neuroscience explores the functional organization and neurophysiology of the human central nervous system, while providing a neurobiological framework for understanding human behavior. In this course, you will discover the organization of the neural systems in the brain and spinal cord that mediate sensation, motivate bodily action, and integrate sensorimotor signals with memory, emotion and related faculties of cognition. The overall goal of this course is to provide the foundation for understanding the impairments of sensation, action and cognition that accompany injury, disease or dysfunction in the central nervous system. The course will build upon knowledge acquired through prior studies of cell and molecular biology, general physiology and human anatomy, as we focus primarily on the central nervous system. This online course is designed to include all of the core concepts in neurophysiology and clinical neuroanatomy that would be presented in most first-year neuroscience courses in schools of medicine. However, there are some topics (e.g., biological psychiatry) and several learning experiences (e.g., hands-on brain dissection) that we provide in the corresponding course offered in the Duke University School of Medicine on campus that we are not attempting to reproduce in Medical Neuroscience online. Nevertheless, our aim is to faithfully present in scope and rigor a medical school caliber course experience. This course comprises six units of content organized into 12 weeks, with an additional week for a comprehensive final exam: - Unit 1 Neuroanatomy (weeks 1-2). This unit covers the surface anatomy of the human brain, its internal structure, and the overall organization of sensory and motor systems in the brainstem and spinal cord. - Unit 2 Neural signaling (weeks 3-4). This unit addresses the fundamental mechanisms of neuronal excitability, signal generation and propagation, synaptic transmission, post synaptic mechanisms of signal integration, and neural plasticity. - Unit 3 Sensory systems (weeks 5-7). Here, you will learn the overall organization and function of the sensory systems that contribute to our sense of self relative to the world around us: somatic sensory systems, proprioception, vision, audition, and balance senses. - Unit 4 Motor systems (weeks 8-9). In this unit, we will examine the organization and function of the brain and spinal mechanisms that govern bodily movement. - Unit 5 Brain Development (week 10). Next, we turn our attention to the neurobiological mechanisms for building the nervous system in embryonic development and in early postnatal life; we will also consider how the brain changes across the lifespan. - Unit 6 Cognition (weeks 11-12). The course concludes with a survey of the association systems of the cerebral hemispheres, with an emphasis on cortical networks that integrate perception, memory and emotion in organizing behavior and planning for the future; we will also consider brain systems for maintaining homeostasis and regulating brain state....
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Cours en ligne à 100 %

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Advanced Level

Niveau avancé

Clock

Recommandé : 8 hours/week

Approx. 89 heures pour terminer
Comment Dots

English

Sous-titres : English

Compétences que vous acquerrez

BrainNeurobiologyNeurologyNeurological Disorders
Globe

Cours en ligne à 100 %

Commencez dès maintenant et apprenez aux horaires qui vous conviennent.
Calendar

Dates limites flexibles

Réinitialisez les dates limites selon votre disponibilité.
Advanced Level

Niveau avancé

Clock

Recommandé : 8 hours/week

Approx. 89 heures pour terminer
Comment Dots

English

Sous-titres : English

Programme du cours : ce que vous apprendrez dans ce cours

1

Section
Clock
2 heures pour terminer

Getting Started in Medical Neuroscience

<p>Let's get started in Medical Neuroscience! Each module in Medical Neuroscience will begin with a brief description like this that provides you with an overview of the module. In this first module, you will get to know something about Prof. White and his career in neuroscience; you will understand the scope of Medical Neuroscience, its learning resources, your responsibilities for maximizing your benefit in this course, and you will learn Prof. White's tips on how best to study and learn.</p><p> At the end of this module, please take the ungraded preliminary quiz, "Are you ready for Medical Neuroscience", to self-assess your background knowledge. Your score on this quiz will not count toward your overall score in this course. However, you should be able to pass this quiz (score 70% or better) if you are ready for the academic challenge of this course. Students who are likely to achieve their goals in Medical Neuroscience should be able to successfully answer nearly all of the quiz questions on their first attempt and feel comfortable with assessment questions at this level of knowledge.</p>...
Reading
5 vidéos (Total 75 min), 2 lectures, 1 quiz
Video5 vidéos
The Scope of Medical Neuroscience11 min
Learning resources for Medical Neuroscience32 min
Your Part!13 min
"Neur-run" with Professor White3 min
Reading2 lectures
Learning Objectives10 min
Your Mentor Team10 min
Quiz1 exercice pour s'entraîner
Preliminary Quiz: Are you ready for Medical Neuroscience?22 min
Clock
2 heures pour terminer

Neuroanatomy: Introducing the Human Brain

Your introduction to Medical Neuroscience continues as you experience in this module a brief introduction to the human brain, its component cells, and some basic anatomical conventions for finding your way around the human central nervous system....
Reading
4 vidéos (Total 79 min), 1 lecture, 1 quiz
Video4 vidéos
Functional Microanatomy of Neurons31 min
Non-Neural Cells of the CNS20 min
Basic Orientation in the Human CNS7 min
Reading1 lecture
Introduction, Learning Objectives and Recommended Reading10 min
Quiz1 exercice pour s'entraîner
Cells of the CNS and Basic Orientation18 min

2

Section
Clock
3 heures pour terminer

Neuroanatomy: Surface Anatomy of the Human CNS

We now begin in earnest our lessons on neuroanatomy with the surface of the human brain, including a brief run through the cranial nerves and the blood supply to the CNS. In this module, you will learn the basic subdivisions of the vertebrate nervous system; however, your focus should be on the cerebral cortex. Along the way, you will be challenged to "build a digital brain" that should help you generate and improve your mental “model” of the cerebral hemispheres of the human brain. Another great way to refine your mental model is through sketching and crafting, so please do the learning objectives that are designed to help you make visible (and tangible) your understanding of the cerebral hemispheres....
Reading
12 vidéos (Total 129 min), 2 lectures, 2 quiz
Video12 vidéos
Medial Surface of the Brain5 min
Finding the Central Sulcus6 min
Ventral Surface of the Brain8 min
Building a Digital Brain (Fingers to Gyri)11 min
Surface Anatomy of the Brainstem4 min
Blood Supply to the Brain15 min
Overview of the Cranial Nerves19 min
Overview of the Spinal Nerves8 min
Localizing the Cranial Nerves13 min
Cranial Nerve Function, part 116 min
Cranial Nerve Function, part 211 min
Reading2 lectures
Learning Objectives / Recommended Readings10 min
Learning Objectives / Recommended Readings10 min
Quiz2 exercices pour s'entraîner
Cerebral Cortex, Brainstem, and Blood Supply24 min
Cranial and Spinal Nerves16 min
Clock
4 heures pour terminer

Neuroanatomy: Internal Anatomy of the Human CNS

...
Reading
12 vidéos (Total 160 min), 2 lectures, 2 quiz
Video12 vidéos
Cranial Nerve Nuclei, part 112 min
Cranial Nerve Nuclei, part 219 min
Cranial Nerve Nuclei, part 317 min
Cranial Nerve Nuclei, part 417 min
Internal Anatomy of the Spinal Cord - Gray and White Matter11 min
Internal Anatomy of the Spinal Cord -Longitudinal Organization11 min
Internal Anatomy of the Spinal Cord In Cross Sections6 min
Ventricles8 min
Overview of the Internal Capsule and Deep Gray Matter8 min
Localizing the Internal Capsule and Deep Gray Matter In Brain Slabs9 min
Localizing the Internal Capsule and Deep Gray Matter In Sylvius Atlases12 min
Reading2 lectures
Learning Objectives / Recommended Readings10 min
Learning Objectives / Recommended Readings10 min
Quiz2 exercices pour s'entraîner
Brainstem and Spinal Cord22 min
Forebrain26 min

3

Section
Clock
3 heures pour terminer

Neural Signaling: Electrical Excitability and Signal Propagation

We now turn our attention from the tangible (human neuroanatomy) to the physiological as we explore the means by which neurons generate, propagate and communicate electrical signals. After exploring those structures in the human brain that are visible to the unaided eye, we must now sharpen our focus and zoom-in, as it were, to the unitary level of organization and function in the central nervous system: to the level of individual neurons and their component parts that are crucial for neural signaling....
Reading
9 vidéos (Total 142 min), 1 lecture, 1 quiz
Video9 vidéos
Ionic Basis of the Resting Membrane Potential, part 114 min
Ionic Basis of the Resting Membrane Potential, part 215 min
Ionic Basis of the Action Potential, part 118 min
Ionic Basis of the Action Potential, part 212 min
Ionic Basis of the Action Potential, part 315 min
Molecular Mechanisms of Action Potential Generation, part 120 min
Molecular Mechanisms of Action Potential Generation, part 29 min
Propagation of Action Potentials20 min
Reading1 lecture
Learning Objectives / Recommended Readings10 min
Quiz1 exercice pour s'entraîner
Generating and Propagating Electrical Signals20 min

4

Section
Clock
5 heures pour terminer

Neural Signaling: Synaptic Transmission and Synaptic Plasticity

Let’s continue our studies of neural signaling by learning about what happens at synaptic junctions, where the terminal ending of one neuron meets a complementary process of another excitable cell....
Reading
13 vidéos (Total 226 min), 2 lectures, 2 quiz
Video13 vidéos
Synaptic Transmission, part 215 min
Neurotransmitters, part 115 min
Neurotransmitters, part 222 min
Ionotropic Neurotransmitters Receptors, part 117 min
Ionotropic Neurotransmitters Receptors, part 211 min
Metabotropic Neurotransmitters Receptors and Postsynaptic Mechanisms11 min
Synaptic Integration25 min
Long-Term Potentiation and Depression, part 122 min
Long-Term Potentiation and Depression, part 217 min
Long-Term Potentiation and Depression, part 314 min
Spike-Timing Dependent synaptic Plasticity19 min
Hebb's Postulate11 min
Reading2 lectures
Learning Objectives / Recommended Readings10 min
Learning Objectives / Recommended Readings10 min
Quiz2 exercices pour s'entraîner
Synaptic Transmission24 min
Synaptic Plasticity18 min
4.9
Direction Signs

56%

a commencé une nouvelle carrière après avoir terminé ces cours
Briefcase

83%

a bénéficié d'un avantage concret dans sa carrière grâce à ce cours

Meilleurs avis

par KRDec 22nd 2016

I have not really taken any Neuroscience courses and I have to say this was very challenging with my already full-time load at school but I did it! Yay! I love Dr. White he is an awesome professor!

par RRNov 25th 2016

While I greatly respect Dr. White's obvious immense knowledge of the neural anatomy, I feel taking this course did very little beyond showing me that perhaps medicine and anatomy wasn't for me.

Enseignant

Leonard E. White, Ph.D.

Associate Professor
Department of Neurology, Department of Neurobiology, Duke University School of Medicine; Department of Psychology & Neuroscience, Trinity College of Arts & Sciences; Director of Education, Duke Institute for Brain Sciences; Duke University

À propos de Duke University

Duke University has about 13,000 undergraduate and graduate students and a world-class faculty helping to expand the frontiers of knowledge. The university has a strong commitment to applying knowledge in service to society, both near its North Carolina campus and around the world....

Foire Aux Questions

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

  • No. Completion of a Coursera course does not earn you academic credit from Duke; therefore, Duke is not able to provide you with a university transcript. However, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile.

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