À propos de ce cours
4.7
94 ratings
26 reviews
A big welcome to “Bioinformatics: Introduction and Methods” from Peking University! In this MOOC you will become familiar with the concepts and computational methods in the exciting interdisciplinary field of bioinformatics and their applications in biology, the knowledge and skills in bioinformatics you acquired will help you in your future study and research. Course materials are available under the CC BY-NC-SA License....
Globe

Cours en ligne à 100 %

Commencez dès maintenant et apprenez aux horaires qui vous conviennent.
Calendar

Dates limites flexibles

Réinitialisez les dates limites selon votre disponibilité.
Clock

Recommandé : 1-2 hours/week

Approx. 18 heures pour terminer
Comment Dots

English

Sous-titres : English
Globe

Cours en ligne à 100 %

Commencez dès maintenant et apprenez aux horaires qui vous conviennent.
Calendar

Dates limites flexibles

Réinitialisez les dates limites selon votre disponibilité.
Clock

Recommandé : 1-2 hours/week

Approx. 18 heures pour terminer
Comment Dots

English

Sous-titres : English

Programme du cours : ce que vous apprendrez dans ce cours

1

Section
Clock
2 heures pour terminer

Introduction and History of Bioinformatics

Welcome to “Bioinformatics: Introduction and Methods! Upon completion of this module you will be able to: become familiar with the essential concepts of bioinformatics; explore the history of this young area; experience how rapidly bioinformatics is growing. Our supplementary materials will give you a better understanding of the course lectures through they are not required in quizzes or exams...
Reading
4 vidéos (Total 69 min), 2 lectures, 1 quiz
Video4 vidéos
History of Bioinformatics30 min
Bioinformatics in Mainland China8 min
About This Course9 min
Reading2 lectures
Readings10 min
Slides10 min
Quiz1 exercice pour s'entraîner
Introduction and History of Bioinformatics20 min

2

Section
Clock
2 heures pour terminer

Sequence Alignment

Upon completion of this module, you will be able to: describe dynamic programming based sequence alignment algorithms; differentiate between the Needleman-Wunsch algorithm for global alignment and the Smith-Waterman algorithm for local alignment; examine the principles behind gap penalty and time complexity calculation which is crucial for you to apply current bioinformatic tools in your research; experience the discovery of Smith-Waterman algorithm with Dr. Michael Waterman himself....
Reading
7 vidéos (Total 99 min), 2 lectures, 1 quiz
Video7 vidéos
Global Alignment by Dynamic Programming14 min
From Global to Local6 min
Alignment with Affine Gap Penalty and Calculation of Time Complexity of The Needleman-Wunsch Algorithm6 min
Interview with M. S. Waterman Waterman29 min
Supplement on Homology & Similarity, Similarity Matrix and Dot Matrix (English Subtitles)10 min
Student Presentation (English Subtitles)18 min
Reading2 lectures
Readings10 min
Slides10 min
Quiz1 exercice pour s'entraîner
Sequence Alignment18 min

3

Section
Clock
1 heure pour terminer

Sequence Database Search

Upon completion of this module, you will be able to: become familiar with sequence databse search and most common databases; explore the algoritm behind BLAST and the evaluation of BLAST results; ajdust BLAST parameters base on your own research project....
Reading
3 vidéos (Total 41 min), 2 lectures, 1 quiz
Video3 vidéos
BLAST Algorithm: A Primer13 min
Student Presentation (English Subtitles)15 min
Reading2 lectures
Readings10 min
Slides10 min
Quiz1 exercice pour s'entraîner
Sequence Database Search10 min

4

Section
Clock
1 heure pour terminer

Markov Model

Upon completion of this module, you will be able to: recognize state transitions, Markov chain and Markov models; create a hidden Markov model by yourself; make predictuions in a real biological problem with hidden Markov model....
Reading
4 vidéos (Total 47 min), 2 lectures, 1 quiz
Video4 vidéos
Hidden Markov Model11 min
Predict with Hidden Markov Model10 min
Student Presentation16 min
Reading2 lectures
Readings10 min
Slides10 min
Quiz1 exercice pour s'entraîner
Markov Model 14 min

Enseignants

Ge Gao 高歌, Ph.D.

Assistant Professor, Principle Investigator
Center for Bioinformatics, School of Life Science

Liping Wei 魏丽萍, Ph.D.

Professor, Director
Center for Bioinformatics, School of Life Sciences

À propos de Peking University

Peking University is determined to make its education openly accessible to students in China and around the world. With over 3000 faculty members, Peking University offers excellence in teaching and learning. Founded in 1898, Peking University (PKU) was the first national comprehensive university in China. For the past 115 years, with its hundreds of thousands of outstanding alumni, Peking University has made prominent contributions in the humanities and sciences to further China's prosperity and progress....

Foire Aux Questions

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

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