À propos de ce cours
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Anglais

Sous-titres : Anglais

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Commencez dès maintenant et apprenez aux horaires qui vous conviennent.

Dates limites flexibles

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Niveau intermédiaire

Approx. 15 heures pour terminer

Recommandé : 4 weeks of study, 4-6 hours a week...

Anglais

Sous-titres : Anglais

Programme du cours : ce que vous apprendrez dans ce cours

Semaine
1
1 heure pour terminer

Welcome to the course

Great that you are joining us! In this course you will learn about clinical kidney, pancreas and islet transplantation and its challenges. Before you start with studying we invite you first go through our introduction module and introduce yourself in the forum to meet your fellow learners. Medical professionals can receive Continuing Medical Education (CME) credit for this course. Information on CME credit and how to obtain credit can be found in our CME credit module. If you encounter any difficulties while studying, please let us know in the forum. For technical difficulties or questions regarding the course certificate, you can always contact the Coursera Learner Helpdesk. Good luck & we hope you enjoy studying in this course!

...
1 vidéo (Total 2 min), 9 lectures
9 lectures
About us: Introduction to the Team5 min
Welcome to Leiden University5 min
Complete our short survey10 min
Tips for studying online5 min
Being successful in an international virtual learning environment5 min
Behaving in an academic way5 min
CME information10 min
How to apply for CME credit10 min
CME FAQs10 min
5 heures pour terminer

Before the Transplant

Welcome to this first module of the course! We will answer important questions before transplantation. These include: why is transplantation the preferred option for patients with end stage renal disease? What are the immunological barriers for transplantation? And what are the selection criteria before transplantation? Unique 3D movies about the different immunological tests will help you to understand the concepts. There are also optional lectures, including a fascinating movie about the Eurotransplant allocation system and patient/donor interviews. At the end of the module we will link the contents you have learned to clinical patient cases, patient - donor interviews and a quiz. You can find each other on the discussion forum. With the e-tivities you can apply your knowledge. In the honors lessons more in depth immunological testing and pre transplant screening can be obtained. The lesson also includes peer reviews about important preclinical questions. Have fun and good luck with the first module!

...
11 vidéos (Total 79 min), 4 lectures, 3 quiz
11 vidéos
The Kidney in Health and Disease5 min
Options if Kidneys Fail5 min
Immunogenetics7 min
Introduction to the Immune System6 min
The Humoral Immune System6 min
Histocompatibility7 min
Cases from Daily Practice - Patient Selection7 min
Eurotransplant Company Film 'More than a Match'13 min
Interview: Transplant Recipient and Donor: Part 110 min
Epitopes6 min
4 lectures
Glossary10 min
References5 min
HLA Epitope Matching is the Future30 min
HLA Antibody Detection: Not All Antibodies are the Same30 min
2 exercices pour s'entraîner
Check your knowledge30 min
Check your knowledge10 min
Semaine
2
8 heures pour terminer

The Procedure and the Patient

Now you know the factors of importance before transplantation, including the immunological barriers and important aspects for patient selection, we can focus on challenged patient groups and on surgical procedures. What does a kidney, pancreas and islet transplantation surgical procedure look like? What is important? And what are the key aspects in elderly patients, patients with diabetes and immunological challenged patients. We have unique visulisations, 360 virtual reality videos and a game about a patient case. Advanced readings will invite you to look at the different subjects in more depth. At the end of the module there are interviews about a patient with diabetes and the transplant recipient and donor to illustrate the impact of life. You can discuss patient cases on the forum together with your peers. In the honors lesson you can apply knowledge about more in depth immunological, surgical and metabolic challenges and living kidney donation. Let’s start and we hope you will enjoy this module.

...
14 vidéos (Total 111 min), 7 lectures, 3 quiz
14 vidéos
Immunological Challenged Patient: ABO Incompatible Transplants6 min
Immunological Challenged Patient: Highly Sensitized Patient6 min
The Diabetic Patient10 min
The Elderly Patient6 min
Organ Procurement and Preservation9 min
Kidney Transplant Surgery7 min
Simultaneous Pancreas Kidney & Islet Transplantation15 min
A: Cases from Daily Practice: Different Choices for Different Diabetic Patients5 min
B: Cases from Daily Practice: Different Choices for Different Diabetic Patients6 min
Interview: Patient with Diabetes14 min
Interview: Transplant Recipient and Donor: Part 24 min
B Cell Replacement and Diabetes Type II11 min
Surgical Challenged Patients6 min
7 lectures
Introduction to Watching 360 VR Videos10 min
Serious Game: A Patient with Immunological Challenges30 min
Glossary10 min
References5 min
Highly Sensitized Patients: The AM Program30 min
Additional Challenged Transplant Recipients30 min
Living Kidney Donation30 min
2 exercices pour s'entraîner
Check your knowledge30 min
Check your knowledge20 min
Semaine
3
10 heures pour terminer

Early Challenges in Transplantation

You are now familiar with the basic knowledge about challenges in transplant recipients and the surgical transplant procedures. Once the transplantation has been successful, it doesn’t mean everything is stable. What are actually the graft survival data? Which challenges do we face in the first months? How can we tackle these challenges? 3D movies about early surgical challenges and about the targets for immunosuppressives, including cell therapy, will help you to understand the concepts. In addition, we invite you to master the advanced knowledge and to give your opinion in the patient cases in the forum. There is also a serious game about a patient case. Can you solve the challenges? And can you think of a scenario for the game and help us with building? We will make a game of the best scenario, which will be incorporated in the course. In the honors lesson you can learn in more detail about immunological concepts, including the complement system. A patient case will help to show you the importance of this knowledge. Good luck with this module and happy learning!

...
12 vidéos (Total 95 min), 9 lectures, 3 quiz
12 vidéos
Surgical Challenges in the Early Period5 min
Ischemia Reperfusion Injury6 min
Cellular Rejection8 min
Antibody Mediated Rejection6 min
Immune Suppression10 min
Novel Therapeutics: Cell Therapy after Transplantation8 min
Cases from Daily Practice A - Patient Cases with Early Challenges6 min
Cases from Daily Practice B - Patient Cases with Early Challenges6 min
Interview Transplant Recipient & Donor: Part 38 min
The Complement System and Transplantation11 min
Cases from Daily Practice: Patient Case with an Early Challenge7 min
9 lectures
Serious Game: Interactive Patient Case30 min
Optional - Immunesuppressive Regimens and Toxicity Profiles1 h
Biomarkers40 min
Therapeutic drug monitoring of immunosuppressive drugs1 h
Glossary10 min
References5 min
A closer Look at Antibody Mediated Rejection30 min
Innate Immunity and Impact on Transplantation30 min
Molecular Insights into Cellular Rejection30 min
2 exercices pour s'entraîner
Check your knowledge20 min
Check your knowledge10 min
Semaine
4
7 heures pour terminer

Late Challenges in Transplantation

Now you’ve learned about the challenges in the early period after transplantation. But what about the late period? What is the long term patient and allograft survival? Have we improved in the last decades? What are the main causes for morbidity and mortality? And can we reach tolerance in the future? We invite you to give your opinion in the patient cases and to discuss it on the forum. There are also advanced readings to look at additional subjects, including recurrence of the kidney disease after transplantation, the organization of dermatological care for the transplant recipient and the role of the patient himself in the whole process. The interview about tolerance gives you insight why pregnancy is of interest to understand the concept of tolerance and which steps have been made from lab research to a clinical protocol. In the honors lesson late challenges will be discussed in more detail, with a focus on infections, recurrence of the kidney disease after transplantation and tolerance. Have fun and good luck with this last module.

...
12 vidéos (Total 96 min), 5 lectures, 6 quiz
12 vidéos
Infections: Overview and CMV infection8 min
Infections: BK and EBV infection7 min
Malignancies8 min
Late Challenges after Pancreas and Islet Transplantation8 min
Post Transplant Diabetes Mellitus8 min
Cardiovascular Disease7 min
Tolerance: Interview with Prof. Claas (LUMC) and Prof. Wood (Oxford)13 min
Cases from Daily Practice A - Patient Cases with Late Challenges5 min
Cases from Daily Practice B - Patient Cases with Late Challenges6 min
Recurrence of Kidney Disease after Transplantation8 min
Vaccination and Transplantation8 min
5 lectures
Pneumocystis jirovecii10 min
Glossary10 min
References5 min
Skin Diseases after Transplantation and Dermatological Aftercare30 min
Tolerance in more Detail30 min
5 exercices pour s'entraîner
Check your knowledge30 min
Patient Case 1: Enhanced Glucose after SPK15 min
Patient Case 2: Hyperglycemia after Islet Transplantation15 min
Patient Case 3: A Complication after Pancreas-alone Transplantation15 min
Check your knowledge20 min
1 heure pour terminer

Final Quiz

We hope you have enjoyed all the modules. Good luck with the final quiz! If you are interested in an intensive course about transplantation go to the course resources.

...
1 lecture, 2 quiz
1 lecture
Complete our short survey10 min
2 exercices pour s'entraîner
Final Exam1 h
Final Honours Exam16 min
4.8
46 avisChevron Right

50%

a commencé une nouvelle carrière après avoir terminé ces cours

30%

a bénéficié d'un avantage concret dans sa carrière grâce à ce cours

11%

a obtenu une augmentation de salaire ou une promotion

Principaux examens pour Clinical Kidney, Pancreas and Islet Transplantation

par SWDec 27th 2016

Wonderful course. Great instruction on very interesting topics. Videos support learning and a good amount of information every week. Thanks for the organization and delivery of this course.

par AEMay 24th 2017

THE BEST COURSE I have taken in COURSERA\n\nGREAT LECTURERS , BEST VIDEOS, AND VERY ORGANIZED\n\n3D movies are really fantastic\n\nHope to join in future sessions to get better scores

Enseignants

Avatar

Marlies Reinders

Prof. Dr.
LUMC, Department of Nephrology and Transplantation
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Frans Claas

Professor
LUMC, Department of Immunohaematology and Blood Transfusion
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Cees van Kooten

Professor
LUMC, Department of Nephrology and Transplantation
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Sebastiaan Heidt

Dr.
LUMC, Department of Immunohaematology and Blood Transfusion
Avatar

Volkert Huurman

Dr.
LUMC, Department of Transplant Surgery
Avatar

Hans de Fijter

Professor
LUMC, Department of Nephrology and Transplantation
Avatar

Eelco de Koning

Professor
LUMC, Department of Nephrology and Transplantation and Endocrinology and Metabolism
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Andre Baranski

Dr.
LUMC, Department of Transplant Surgery
Avatar

Ton Rabelink

Professor
LUMC, Department of Nephrology and Transplantation
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Aiko de Vries

Dr.
LUMC, Department of Nephrology and Transplantation
Avatar

Jan Nico Bouwes Bavinck

Dr.
LUMC, Department of Dermatology
Avatar

Leo Visser

Professor
LUMC, Department of Infectious Diseases
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Ingeborg Bajema

Dr.
LUMC, Department of Pathology

À propos de Université de Leyde

Leiden University is one of Europe's foremost research universities. This prominent position gives our graduates a leading edge in applying for academic posts and for functions outside academia. Leiden University is the oldest university in the Netherlands. It was founded in February 1575, as a gift from William of Orange to the citizens of Leiden after they had withstood a long siege by the Spanish. Our motto is: Praesidium Libertatis — Bastion of Liberty....

À propos de Centre médical universitaire de Leiden

Foire Aux Questions

  • Une fois que vous êtes inscrit(e) pour un Certificat, vous pouvez accéder à toutes les vidéos de cours, et à tous les quiz et exercices de programmation (le cas échéant). Vous pouvez soumettre des devoirs à examiner par vos pairs et en examiner vous-même uniquement après le début de votre session. Si vous préférez explorer le cours sans l'acheter, vous ne serez peut-être pas en mesure d'accéder à certains devoirs.

  • Lorsque vous achetez un Certificat, vous bénéficiez d'un accès à tout le contenu du cours, y compris les devoirs notés. Lorsque vous avez terminé et réussi le cours, votre Certificat électronique est ajouté à votre page Accomplissements. À partir de cette page, vous pouvez imprimer votre Certificat ou l'ajouter à votre profil LinkedIn. Si vous souhaitez seulement lire et visualiser le contenu du cours, vous pouvez accéder gratuitement au cours en tant qu'auditeur libre.

  • Continuing Medical Education (CME) consists of educational activities that aim to maintain, develop, or increase the knowledge, skills, and professional performance in order to maintain competence and learn about new and developing areas of the medical field. Content for these programs is developed, reviewed, and delivered by faculty who are experts in their individual clinical areas. In various countries, a certain amount of CME-credit hours must be obtained by medical professionals to maintain their licenses.

    For this course it is possible to obtain 5, 9 or 13 CME credit points. For more information on how to obtain these points we like to refer to the "Additional introduction for obtaining CME credit" module in week 1 of the course

  • Yes, if you have already done the course previously and obtained the Coursera official Course Certificate as proof we encourage you to apply for the CME credits. You can obtain 5 or 9 CME as follows:

    1. Sign up for the course at “Boerhaave Continuous Medical Education” (https://www.boerhaavecontinuousmedicaleducation.com/)

    2. Upload your Verified Certificate from Coursera (without honors 5 CME or with honors 9 CME). Pay the contribution according to “Boerhaave Continuous Medical Education." They will provide you with the instructions and add the CME credits to GAIA (Dutch participants) and/or provide you with a CME certificate (international participants)

D'autres questions ? Visitez le Centre d'Aide pour les Etudiants.